Intramural plasminogen activator inhibitor type-1 and coronary atherosclerosis.
نویسندگان
چکیده
Altered expression of plasminogen activator inhibitor type-1 in vessel walls, reviewed here, might affect coronary atherogenesis. Upregulation might exacerbate vasculopathy by potentiating thrombosis and by inhibiting vascular smooth muscle cell migration, resulting in attenuation of thickness of elaborated fibrous caps implicated in the vulnerability of atheroma to rupture.
منابع مشابه
Serum Level of Plasminogen Activator Inhibitor Type-1 in Addicted Patients with Coronary Artery Disease
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ورودعنوان ژورنال:
- Arteriosclerosis, thrombosis, and vascular biology
دوره 23 11 شماره
صفحات -
تاریخ انتشار 2003